Product Name :
OGG1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
8 hydroxyguanine DNA glycosylase antibody 8 oxoguanine DNA glycosylase 1 antibody 8 oxoguanine DNA glycosylase antibody AP lyase antibody DNA (apurinic or apyrimidinic site) lyase antibody DNA apurinic or apyrimidinic site lyase antibody DNA lyase antibody DNA-(apurinic or apyrimidinic site) lyase antibody HMMH antibody HOGG 1 antibody 展开
Function :
DNA repair enzyme that incises DNA at 8-oxoG residues.2169908-22-7 custom synthesis Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3′ to the lesion. Defects in OGG1 may be a cause of renal cell carcinoma (RCC). It is a heterogeneous group of sporadic or hereditary carcinoma derived from cells of the proximal renal tubular epithelium. It is subclassified into clear cell renal carcinoma (non-papillary carcinoma), papillary renal cell carcinoma, chromophobe renal cell carcinoma, collecting duct carcinoma with medullary carcinoma of the kidney, and unclassified renal cell carcinoma.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within Human OGG1 aa 269-345 / 345.7-Bromo-1H-pyrazolo[3,4-c]pyridine In stock
Species reactivity:
Human, Mouse
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
AB_3073398
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33448748 Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 39 kDa
Positive control :
F9 cell lysate, mouse kidney tissue lysate, human liver tissue, human liver cancer tissue, human kidney tissue.