Product Name :
Neuropilin 1 Mouse Monoclonal Antibody [A3-D1]
Predicted band size :
Observed band size :
Synonyms:
AI851453 antibody BCTL1 antibody Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 1 antibody Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1 antibody BTCL1 antibody C130005O10Rik antibody FLJ41325 antibody Neto1 antibody NETO1_HUMAN antibody Neuropilin and tolloid like 1 antibody 展开
Function :
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulate VEGF-induced angiogenesis. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein with mouse Neuropilin 1 aa 856-923 / 923.
Species reactivity:
Human, Mouse
Verify application:
WB, IF-Cell, IHC-P
Coupling :
unconjugated
Clone number:
A3-D1
RRID:
AB_3073005
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃.620960-38-5 Data Sheet Avoid repeated freeze / thaw cycles.Formula of Tetrabenzyl pyrophosphate
Storage buffer solution:
1*PBS (pH7.PMID:33637620 4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgM
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 103 kDa
Positive control :
Hela, mouse brain tissue, Human kidney tissue, mouse kidney tissue.