Product Name :
1,2-Diethylbenzene (CAS 135-01-3)
Synonym :
Application :
1,2-Diethylbenzene is a building block for synthesis
CAS:
135-01-3
Purity:
Molecular Weight:
134.22
Formula :
C10H14
Physical state:
Liquid
solubility :
Soluble in alcohol, benzene, and carbon tetrachloride. Insoluble in water.
Shipping Condition :
Store at room temperature
Melting point:
-31.1° C (lit.)
SMILES:
CCC1=CC=CC=C1CC
References:
:Assessment of the developmental toxicity and placental transfer of 1,2-diethylbenzene in rats. | Saillenfait, AM., et al. 1999. Food Chem Toxicol. 37: 1089-96. PMID: 10566880Toxicokinetics of 1,2-diethylbenzene in male Sprague-Dawley rats-part 1: excretion and metabolism of [(14)C]1,2-diethylbenzene. | Payan, JP., et al. 1999. Drug Metab Dispos. 27: 1470-8. PMID: 10570029Toxicokinetics and metabolism of 1,2-diethylbenzene in male Sprague Dawley rats–part 2: evidence for in vitro and in vivo stereoselectivity of 1,2-diethylbenzene metabolism. | Payan, JP., et al. 2001. Drug Metab Dispos. 29: 868-76. PMID: 11353756Aromatic as well as aliphatic hydrocarbon solvent axonopathy. | Spencer, PS., et al. 2002. Int J Hyg Environ Health. 205: 131-6. PMID: 12018006A liquid chromatographic-mass spectrometric method to evaluate the distribution kinetics of 1,2-diethylbenzene and its metabolite 1,2-diacetylbenzene in the F344 male rat.1166831-45-3 web | Thrall, KD.BuyNH2-PEG5-C2-NH-Boc , et al. 2007. J Toxicol Environ Health A. 70: 67-72. PMID: 17162499Environmental metabolite, 1,2-diacetylbenzene, produces cytotoxicity through ROS generation in HUVEC cells. | Kim, MK., et al. 2007. J Toxicol Environ Health A. 70: 1336-43. PMID: 17654252Using supercritical fluid chromatography to determine diffusion coefficients of 1,2-diethylbenzene, 1,4-diethylbenzene, 5-tert-butyl-m-xylene and phenylacetylene in supercritical carbon dioxide. | Pizarro, C., et al. 2007. J Chromatogr A. 1167: 202-9. PMID: 17850810Bio-distribution study of 1,2-diethylbenzene and its main metabolites by whole-body autoradiography and tissue homogenates.PMID:33689102 | Payan, JP., et al. 2008. Arch Toxicol. 82: 591-600. PMID: 18253718Probing mechanisms of axonopathy. Part I: Protein targets of 1,2-diacetylbenzene, the neurotoxic metabolite of aromatic solvent 1,2-diethylbenzene. | Tshala-Katumbay, D., et al. 2008. Toxicol Sci. 105: 134-41. PMID: 18502740Possible involvement of 1,2-diacetylbenzene in diethylbenzene-induced neuropathy in rats. | Gagnaire, F., et al. 1991. J Appl Toxicol. 11: 261-8. PMID: 1939999Diethylbenzene-induced sensorimotor neuropathy in rats. | Gagnaire, F., et al. 1990. J Appl Toxicol. 10: 105-12. PMID: 2362075Olfactory mucosal necrosis in rats following acute intraperitoneal administration of 1,2-diethylbenzene, 1,2-diacetylbenzene and 2,5-hexanedione. | Gagnaire, F. and Boucard, S. 2014. Neurotoxicology. 41: 9-19. PMID: 24373906Age-Dependent Sensitivity to the Neurotoxic Environmental Metabolite, 1,2-Diacetylbenzene. | Hoang, NMH., et al. 2021. Biomol Ther (Seoul). 29: 399-409. PMID: 33820880