Product Name :
c-Kit Recombinant Rabbit Monoclonal Antibody [ST04-99]
Predicted band size :
110 kDa
Observed band size :
110-140 kDa
Synonyms:
C Kit antibody c-Kit antibody c-Kit Ligand antibody CD117 antibody Kit antibody Kit Ligand antibody KIT oncogene antibody KIT proto oncogene receptor tyrosine kinase antibody KIT_HUMAN antibody Mast cell growth factor receptor antibody 展开
Function :
The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within C-terminal human KIT.
Species reactivity:
Human
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
ST04-99
RRID:
AB_3069869
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.5-Bromo-1-cyclopropyl-1H-pyrazole Chemscene Aliquot store at -20℃ or -80℃.tert-Butyl oct-7-yn-1-ylcarbamate site Avoid repeated freeze / thaw cycles.PMID:33458886
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 110 kDa
Positive control :
Human brain tissue lysates, Saos-2 cell lysate, human breast tissue, human gastrointestinal stromal tumor tissue.