Product Name :
3,5,6-Trichloro-2-pyridinol (CAS 6515-38-4)
Synonym :
2-Hydroxy-3,5,6-trichloropyridine
Application :
CAS:
6515-38-4
Purity:
Molecular Weight:
198.43
Formula :
C5H2Cl3NO
Physical state:
Solid
solubility :
Soluble in water (slightly), DMSO, and methanol.
Shipping Condition :
Store at room temperature
Melting point:
175-177° C
SMILES:
C1=C(C(=O)NC(=C1Cl)Cl)Cl
References:
:Analysis of 3,5,6-trichloro-2-pyridinol in urine samples from the general population using gas chromatography-mass spectrometry after steam distillation and solid-phase extraction. | Koch, HM. and Angerer, J. 2001. J Chromatogr B Biomed Sci Appl. 759: 43-9. PMID: 11499628Biodegradation of chlorpyrifos and 3,5,6-trichloro-2-pyridinol by Cupriavidus sp. DT-1. | Lu, P., et al. 2013. Bioresour Technol. 127: 337-42. PMID: 23131657Predictors of urinary levels of 2,4-dichlorophenoxyacetic acid, 3,5,6-trichloro-2-pyridinol, 3-phenoxybenzoic acid, and pentachlorophenol in 121 adults in Ohio. | Morgan, MK. 2015. Int J Hyg Environ Health. 218: 479-88. PMID: 25891895Photochemical fate and photocatalysis of 3,5,6-trichloro-2-pyridinol, degradation product of chlorpyrifos. | Žabar, R., et al. 2016. Chemosphere. 144: 615-20. PMID: 26398927Degradation of 3,5,6-trichloro-2-pyridinol by a microbial consortium in dryland soil with anaerobic incubation.928-90-5 supplier | Wang, S., et al. 2019. Biodegradation. 30: 161-171. PMID: 30929106NanoFe3O4 accelerates anoxic biodegradation of 3, 5, 6-trichloro-2-pyridinol. | Zhang, C., et al. 2019. Chemosphere. 235: 185-193. PMID: 31255759Biochar amendment effectively reduces the transport of 3,5,6-trichloro-2-pyridinol (a main degradation product of chlorpyrifos) in purple soil: Experimental and modeling. | Lei, W., et al. 2020. Chemosphere. 245: 125651. PMID: 31881382Acute toxicity of chlorpyrifos and its metabolite 3,5,6-trichloro-2-pyridinol alone and in combination using a battery of bioassays. | Echeverri-Jaramillo, G., et al. 2020. Environ Sci Pollut Res Int. 27: 32770-32778. PMID: 32519098Cytotoxic and estrogenic activity of chlorpyrifos and its metabolite 3,5,6-trichloro-2-pyridinol. Study of marine yeasts as potential toxicity indicators.95464-05-4 Description | Echeverri-Jaramillo, G.PMID:33438524 , et al. 2021. Ecotoxicology. 30: 104-117. PMID: 33249537Novel degradation pathways for Chlorpyrifos and 3, 5, 6-Trichloro-2-pyridinol degradation by bacterial strain Bacillus thuringiensis MB497 isolated from agricultural fields of Mianwali, Pakistan. | Ambreen, S. and Yasmin, A. 2021. Pestic Biochem Physiol. 172: 104750. PMID: 335180433,5,6-trichloro-2-pyridinol intensifies the effect of chlorpyrifos on the paracrine function of Sertoli cells by preventing binding of testosterone and the androgen receptor. | Gao, H., et al. 2021. Toxicology. 460: 152883. PMID: 34352351The Role of CYP2B6*6 Gene Polymorphisms in 3,5,6-Trichloro-2-pyridinol Levels as a Biomarker of Chlorpyrifos Toxicity Among Indonesian Farmers. | Liem, JF., et al. 2022. J Prev Med Public Health. 55: 280-288. PMID: 356780023,5,6-Trichloro-2-pyridinol confirms ototoxicity in mouse cochlear organotypic cultures and induces cytotoxicity in HEI-OC1 cells. | Huang, M., et al. 2023. Toxicol Appl Pharmacol. 116612. PMID: 37463651